The expression patterns of genes with known or putative functions suggest the relative importance of these genes during pathogenesis.
Our results showed that parkin plays a critical role for regulating p62 stability and implied that dysregulation of parkin/p62 axis could account for the selective vulnerability during pathogenesis of PD.
A battery of morphological and biochemical assays have been conducted showing that hepatitis C virus (HCV) causes an unfolded protein response-dependent incomplete ATG7-mediated autophagy during pathogenesis in human hepatoma cells (Sir et al., 2008).
Histoplasma capsulatum (Hc), a cosmopolitan dimorphic fungal pathogen, express Hsps that participate during pathogenesis [6].
This suggests that XacPNP serves the pathogen to maintain host photosynthetic efficiency during pathogenesis.
In fact, the concentration of EdTx, CT, and CyaA in circulating fluids during pathogenesis is not yet known.
What other genes in V. cholerae might be interacting with hlyA gene during pathogenesis of C. elegans infection?
As shown in Figure 7A, neither nrdEF (PI = 2.1) nor nrdDG (PI = 3.99) seemed to be involved in dNTP synthesis during pathogenesis.
Although we have implicated thirteen contingency loci in host adaptation and enhanced virulence, the functions during pathogenesis of these altered loci are not well established.
pneumoniae strains (WCH16, WCH43 and D39) during pathogenesis.
Finally, we observed increased chondrocyte hypertrophy during pathogenesis.
