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Since Mtb's proteome differs qualitatively and quantitatively during bacterial replication stages from that expressed during dormancy, improved TB vaccines should drive immune responses to Mtb antigens expressed during multiple stages of infection.
We found that Tim bound directly to Plk1 protein in vitro (Fig. 1D and E) and colocalized with Plk1 during multiple stages of M phase in vivo (Fig. 2).
The association of SUMO with the chromosomes throughout mitosis and its localization to the midbodies during anaphase and telophase is consistent with our observation that SUMO plays critical roles during multiple stages of the mitotic cycle.
The pdm genes are expressed during multiple stages of development.
The important role of TGF-β during multiple stages of cancer progression has been widely reported.
These results suggest that physiologically important signaling proteins such as spliceosomal proteins expanded during multiple stages of evolution.
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For example, the addition of Time-of-flight (TOF), Fourier Transform Ion Cyclotron Resonance (FT-ICR) and Orbitrap mass analyzers to an ion trap (IT) has greatly increased the accuracy of measurements during the multiple stages of mass spectrometric (MSn) analysis [6] [9].
These were ranked as targets of particular interest based on evidence of activity during the multiple stages of P. falciparum life cycle studied and/or the presence in SuperTarget database [ 29] as candidates for treatment of other infections [ 12].
The most commonly used transgenic mouse models that develop metastatic mammary cancer are summarized in Table 2. Investigating the functional role of distinct genes during the multiple stages of breast carcinogenesis requires the ability to modulate their function in time and space [ 37].
The best understood system in this respect is the budding yeast Saccharomyces cerevisiae, where septins form a ring structure that undergoes multiple stages of remodeling during the cell cycle.
Due to multiple stages of fluids-formation reactions during sandstone acidizing, the success rate to remove the damage is generally not according to the requirement.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com