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It is crucial for cellular/organismal homeostasis during lifespan that molecular systems can adapt and retain functionality despite long-term variation of environment.
We have found that circadian gene-mutant mice share common aging and cancer-prone phenotypes although these symptoms may be more evident at different times during lifespan or under different physiological conditions in different mouse models.
Such cells must undergo geroconversion during lifespan.
Bones undergo constant remodeling during lifespan.
The symptoms may change during lifespan, hyperactivity becoming less common in adulthood.
It is postulated that ROS, which form endogenously from metabolism, induce intracellular oxidative stress that increases during lifespan and is mechanistically implicated in various aging phenotypes.
Similar(36)
Moreover, health habits established in childhood may be sustained throughout life, more so than those acquired during any other period during the lifespan [ 5- 7].
As RR regulars know, the slot has been through different iterations during its lifespan.
Cherished handmade possessions can be repaired and reused, gathering memories and meaning during their lifespan.
The agency confirmed to the Guardian that the document was still in effect during the lifespan of the controversial rendition, detention and interrogation program.
Mating may occur anytime during the lifespan of the adult female, and in some species she retains fertilized eggs in her body until weather conditions are suitable.
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