Sentence examples for during leading edge from inspiring English sources

These findings significantly contribute to our understanding of the cross-talk between the membrane and the actin cytoskeleton during leading edge protrusion of migrating cells.

In this study, we used a combination of time-lapse fluorescence imaging of living cells and EM to investigate the structure and dynamics of filopodia induced by the I-BAR domain from IRSp53, which is one of the best studied I-BAR-containing proteins playing a key role during leading edge protrusion [21], [22].

One of the most important phenomena that occurs during insect flight is leading edge suction.

They are linked to a number of aspects of cell motility including membrane cytoskeleton adhesion and transport of actin towards the leading edge during cell migration (Fan et al., 2012; McConnell and Tyska, 2010).

Additionally, the number of cells with Golgi localized between the nucleus and leading edge during wound closure was significantly less after STAT5b knockdown (data not shown), suggestive of a defect in cell polarity.

We first measured paxillin dynamics in the cytoplasm, where it is present as single molecules or in very small aggregates, and then measured paxillin binding and unbinding to adhesions at various loci in the cell, including adhesions near the leading edge during their assembly and disassembly.

The Columbia and its crew were lost because a 1.67-pound piece of insulating foam that had fallen off the external tank during liftoff crashed through the leading edge of the shuttle's left wing.

Results on the latter have revealed a significant decrease in the static temperature and pressure during flow acceleration along the leading edge of the impeller blades.

In our findings, it remains elusive whether filopodia appeared first and some of them guided the formation of lamellipodia or if lateral filopodia were probing microenvironment during cell migration toward the leading edge (where the lamellipodia is).

Calculation of the total charge transferred during the time while the leading edge of the stimulus traversed the cell's receptive field, indicates that the SBAC receives a greater amount of excitation during centrifugal stimulation relative to centripetal stimulation.

Long considered a hallmark of apoptosis, blebs have been taking an increasingly central stage in the migration field over the past decade, as it became apparent that they are a widespread leading edge protrusion during cell migration, both in cell culture and in vivo (reviewed in [ 1,2]).