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The RPE65-related phenotype proved to be typically associated with a fundus appearance which is essentially normal during first years and displays only later on fundus alterations which are initially mild.
After additional adjustment for cotinine level during first years of life, prenatal exposure to tobacco constituents significantly affects child motor abilities at age of two (β = −2.6; P = 0.02) (Table 4).
This might indirectly document that, independently from the diagnosis of ALL and its treatment, environmental factors as a negative lifestyle acquired in the family setting during first years of life may intervene in the development of obesity during and after the treatment of ALL.
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OnabotulinumtoxinA (OnabotA) is effective in Chronic Migraine (CM) during first year of treatment and longer.
Most of these patients had improved between 30 and 50% during first year of treatment.
The principal difference between the two successive years was the low number of infected eggs during first year, in all the treatments.
Also after discharge, they were followed up monthly for six months and then every two months, during first year of life.
Kidney function increased during first year post-transplant.
Modern Intrauterine device (IUCD) is very safe, highly effective (99%) during first year [ 1] and inexpensive family planning method [ 2].
However, we observed that exposures during first year of life may contribute differently to the potential load of sensitization.
By contrast, the market has gone down more often than it has risen during second years of terms.
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