Sentence examples for during dosage from inspiring English sources

The denaturation with consequent loss in biological activity of macromolecules during dosage form design and gastrointestinal passages have compelled the scientists to search for alternative methods for the design of delivery devices.

By contrast, X-enrichment of H4K20me1 and depletion of H4K16ac during dosage compensation is DCC- (therefore condensin-) dependent [ 49].

In this study, we present experimental evidence linking condensin-mediated chromosome compaction to chromosome-wide repression of gene expression during dosage compensation.

Up-regulation in males is less effective for X-linked genes since they are already hypertranscribed during dosage compensation [ 15, 16].

Drosophila roX RNAs work in combination with the Male Specific Lethal (MSL) complex to up-regulate expression of X-chromosome linked genes in trans during dosage compensation in male flies [ 96].

Especially during the dosage up-titration period, adverse drug reactions (mainly gastrointestinal) occur that usually cease later in the course [ 38].

Therefore, like transdermal fentanyl, it is again important to provide immediate release opioid medication to assist in the prevention of withdrawal symptoms during initial dosage titration and for treatment of breakthrough pain.

Systemic exposure to tazarotene and tazarotenic acid was measured through maximum plasma concentration (Cmax), time to Cmax, through concentration in plasma, elimination half-life, and areas under the plasma concentration time curve from time zero to time of last measurable concentration and during a dosage interval (AUCs).

Undesirable changes in the pharmaceutical products induced by UV VIS irradiation may occur not only during the production of active pharmaceutical ingredient (API), but also during the preparation of dosage form or during storage [15 17].

The trial was divided into two periods: eight weeks during which the dosage was escalated and then fixed, and six weeks during which variable dosages were used.

These investigators went on to demonstrate that the EM scope allowed accurate loop assessment and scope straightening during colonoscopy, but did not result in a reduction of sedation dosage during colonoscopy when the overall medication doses were small [ 10].