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Cdx2 transcripts preferentially localize apically at the late eight-cell stage and become inherited asymmetrically during divisions that set apart pluripotent and differentiating cells.
To determine whether this might be so in the mouse embryo, we followed the segregation of Cdx2 transcripts during divisions that generate cells of distinct fates.
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And how do a cell's chromosomes manage to pair up and separate during division?
Septal cell wall formation during division must be coordinated with other processes of cell division, such as membrane invagination, DNA replication, and chromosome segregation.
For example, cortex contractility plays a crucial role in amoeboid migration of metastatic cells [6] and during division, where its misregulation can lead to aneuploidy [7].
Late Golgi fragments are often observed in cells during division.
Genome stability relies on the accurate partitioning of chromosomes into the daughter cells during division.
Fully 80.8% of HFF-shp53+GpIbα cells with abnormal filamin A localization showed blebbing during division.
Because germ-line mutations occur during division of germ cells, the probability of mutations increases with the number of divisions.
In proliferating populations, average lipofuscin levels are maintained by the dilution of accumulated lipofuscin to each daughter cell during division.
Nearly all species deposit nascent PG at midcell during division.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com