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The concept that genetic changes accumulate during development and progression of cancer is widely accepted.
Our results indicate an important role of TACE and TIMP3 during development and progression of HNSCCs.
Subtelomeric regions dynamically change their epigenetic pattern during development and progression of several malignancies and degenerative disorders.
We hypothesize that aberrant methylation of miR CpG islands may occur during development and progression of cancers.
Baudino TA, McKay C, Pendeville-Samain H, Nilsson JA, Maclean KH, White EL, et al. c-Myc is essential for vasculogenesis and angiogenesis during development and tumor progression.
Our findings suggest a new function of hCLP46 in modulating critical TGF-β/Smad3-regulated processes during development and tumor progression.
Snail plays an important role in the epithelial-to-mesenchymal transition during development and in tumor progression.
Future studies should probe the functions of non-CpG methylation during the development and progression of breast cancer.
These epigenetic regulatory mechanisms have been found substantially altered during cancer development and progression.
These changes occurred relatively early during the development and progression of hypertrophy.
This process allowed us to identify pathways that are deregulated during HCC development and progression.
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