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DUESs might also not be that advantageous, thus representing a sort of 'lucky DNA' probably driven to overrepresentation in genomic locations where they cause insignificant loss of fitness due to a possibly coincidental specificity of the protein that binds DNA (i.e., receptor) at the cell surface during competence.
In S. pneumoniae two lytic enzymes, namely LytA and CbpD, are specifically induced during competence 39.
In pneumococci, transformation takes place at mid cell, during which EndA is specifically recruited to this area during competence 51.
Hertzberg et al previously showed a significant increase in the percentage of depicted anatomic landmarks on ultrasonography from 33% after 50 ultrasonography examinations to 57% after 200 ultrasonography examinations by radiological residents during competence tests.
Recent work published by our group presented a visualization of short, plaited pilus structures formed on the bacterial cell surface during competence, and rapidly released from the bacteria 9. Pilus shedding directly correlated with transformability, which led to the proposal of the "Hole in the wall" model (Fig. 4).
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DUESs themselves might be a sort of 'lucky DNA' driven to genomic overrepresentation, in the susceptible parts of the genome, not due to any other function but the possibly coincidental specificity of the receptor that binds DNA for uptake during natural competence for transformation.
In the present study we were able to identify orthologous genes exhibiting similar expression profiles in the somatic cells surrounding the oocyte during developmental competence acquisition in vertebrates.
Together, these observations suggest an important, yet unsuspected, role of the Cnih family in the somatic compartment of the follicle during oocyte competence acquisition in tetrapods.
Together, our results demonstrate that tetrapods share a large number of common molecular actors from somatic origin that have similar expression profiles during developmental competence acquisition.
Together, this suggests an important role of the KLF family in vertebrate oogenesis and a conserved pattern of Klf13 expression in the somatic compartment during intrafollicular competence acquisition.
Autolysis in S. pneumoniae seems to be a phenomenon by which a subset of the bacterial population die during the competence status, which is advantageous for surviving cells, as many virulence factors that help invasion are released [ 48, 49].
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