Your English writing platform
Discover LudwigSuggestions(1)
Exact(3)
Temperature of the graft was always below 8°C during cold preservation.
Bioflavonoids attenuate renal proximal tubular cell injury during cold preservation in Euro-Collins and University of Wisconsin solutions.
For instance, a study on endothelial cells submitted to hypothermia showed that the UPS pathway was activated during cold preservation of endothelial cells, but proteasome inhibition could not prevent cell damage [ 6].
Similar(57)
However, during liver cold preservation, a direct effect needs to be established.
HR of steatotic livers by insufflation of gaseous oxygen via the cava vein during the last 90 minutes of cold preservation of the graft has limited mitochondrial dysfunction and restored basal rates of hepatocellular autophagy in rats [ 30].
After 24 h of cold preservation, steatotic livers were removed from preserved solution and flushed at room temperature with 20 mL of Ringer Lactate solution to eliminate the metabolite waste accumulated during liver storage.
Accumulating evidence suggested perturbations at the endoplasmic reticulum (ER) as novel subcellular effectors, possibly involved in the promotion of cell death during cold organ preservation.
Cold ischemia is observed during liver transplantation in which the graft is subjected to warm and cold ischemia followed by a warm reperfusion phase; the warm/cold ischemia sequence is due to vascular occlusion of the liver graft during its procurement from the donor and to graft storage in cold preservation solutions before liver transplantation [ 2, 10].
Cold chains are sometimes used for products which do not require cold preservation.
We designed this study to investigate whether the administration of FK409 during reperfusion ameliorated ischemia-reperfusion injury and enhanced post-transplant graft function in orthotopic heart transplantation following 12-hour cold preservation in a canine model.
Even hypothermic machine perfusion, which has been designed to deliver cold preservation solution into the organ via the circulation, may be incapable of delivering adequate oxygen to an organ during preservation, particularly when the perfusate does not have substantially higher oxygen carrying capacity than water and it is not saturated with a gas containing higher oxygen fraction than air.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com