Multiplex PCR via general primer sites carries the potential for competition during amplification, with a cumulative increase in background, which reduces assay sensitivity.
The risk of colonization increases at a steady rate during hospitalization, suggesting a cumulative daily risk of exposure to C. difficile, probably as spores, which can persist for months in the hospital environment [ 8, 9].
7 While the total number of circumcisions conducted doubled during 2013, reaching a cumulative total of approximately 6 million, this only represents close to 30% of the initial target coverage level in the priority countries.
For the 21 young debutantes during the year 2012-13, a cumulative total of more than 6,400 hours of service assisted people less fortunate in this affluent part of America.
Buffalo had been one of the least-successful programs in college football from their transition to Division I-A in 1999 to 2006, during which they had a cumulative record of 12 79.
Each mouse therefore received during these 22 doses a cumulative dose of either 19.8 or 39.3 mg/kg of 6-TG, or 58.1 mg/kg of AZA, respectively.
Although each of these compounds is characterized by different biological activity and interaction with various target protein molecules (Fig. 2), the end result of their combined action during PCC induction shows a cumulative effect.
We calculated the cumulative incidence of a diagnosis for dementia during follow-up using a cumulative incidence competing risks (CICR) method [ 21], since mortality precludes subsequent diagnosis of dementia and using the Kaplan-Meier method for a time-to-event analysis would overestimate the rate of dementia during the follow-up [ 22].
Parental education may contribute to adult oral health during a critical period, while education may also have a cumulative effect during the life course as well as having a proximal effect in terms of mobility and adult oral health [ 5].
In the present study, non-opioid substance use was defined as a regular and/or maladaptive use pattern during a lifelong cumulative period longer than a year.
