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However, the study was seriously hampered in that there were insufficient data to determine if the variations in PPI dosages and durations of therapy affected the sensitivity of the test.
Patients chronically infected with hepatitis C virus (HCV) require significantly different durations of therapy and achieve substantially different sustained virologic response rates to interferon-based therapies, depending on the HCV genotype with which they are infected.
The urgent need to develop new antitubercular drugs is due to the increasing rate of appearance of multi-drug resistant strains to the commonly used drugs, and the longer durations of therapy and recovery, particularly in immuno-compromised patients.
The development of MDR strains to commonly used drugs is due to, longer durations of therapy as results of resistance, and the resurgence of the disease in immune compromised patients.
Patients were randomly assigned to groups that received standard duration (24 wk; n = 68) or variable durations of therapy.
Moreover, different viral genotypes require different choice and durations of therapy.
Similar(22)
In summary, we identified cumulative AUC and duration-of-therapy thresholds as predictors of amikacin ototoxicity.
Select the most appropriate empiric antimicrobial choice and duration of therapy for common outpatient bacterial infections.
The best drug, the optimal dose and duration of therapy for a particular patient are not determined directly by a study involving a large population".
National guidelines will be reviewed with emphasis on the most appropriate empiric antibiotic choice and duration of therapy.
Thus, defining the optimal duration of therapy has significant implications for patient safety and cost.
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