Frequency and duration were obtained wherever possible, but they were not systematically measured for the different components due to measurement difficulties, poor recall, and inconsistent reporting.
We therefore conducted additional data collection visits in pharmacies wherever possible for the duration of the study.
Modeling is expected to be performed wherever possible and appropriate, e.g. for study duration, patient population, choice of comparator, and type of outcomes.
Integrated measures for each pollutant were collected for one week per season per home wherever feasible, in two sessions of 3 to 4 days duration, averaged to one mean concentration per home per season for our LUR analysis.
The duration of delay reported in weeks or months was transformed in number of days wherever necessary.
Modeling is not acceptable for benefit assessment in Germany but is expected to be performed for HTA in England wherever possible and appropriate, e.g. for study design features such as study duration, patient population, choice of comparator, and type of outcomes.
Because of the long duration of tuberculosis treatment and possible associated adverse events, a microbiologic diagnosis of tuberculosis should be sought wherever possible [ 30].
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