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The OS, PFS and lenalidomide transfusion independence response duration were estimated using the time-to-event approach.
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Secondly, cycle duration was estimated using published microbial reef growth rates.
In three studies [24, 25, 34], all from the same centre, the duration was estimated using the duration of the videocassette recording of the scan.
OI free duration was estimated using the actuarial life table and Kaplan Meier survival.
Pregnancy duration was estimated using the date of the last menstrual period (LMP) or ultrasound if it differed from the LMP based estimate by >2 weeks.
The weighted average chemoprophylaxis effectiveness for each purpose and travel duration was estimated using published values of 92.6%–95.8% (Table 1) [ 11– 13].
In the Swedish Medical Birth Register, pregnancy duration is estimated using a number of variables: date of last menstrual period, estimated date of delivery (from second-trimester ultrasound scan) and pregnancy duration as stated in the paediatric record.
Gestational duration was estimated using the date of last menstrual period (LMP) (Slama et al. 2008) or gestational duration assessed by the obstetrician if it differed from the LMP-based estimate by > 2 weeks.
Survival probabilities and durations were estimated using the Kaplan-Meier method.
The duration of treatment and the duration of interruption were estimated using the Kaplan-Meier method.
Time to PSA progression and duration of survival were estimated using Kaplan Meier technique.
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