Sentence examples for duration prolongation from inspiring English sources

Hondeghem, L. M., Carlsson, L. & Duker, G. Instability and triangulation of the action potential predict serious proarrhythmia, but action potential duration prolongation is antiarrhythmic.

There was no relationship between SA-QRS duration prolongation and dialysis-induced changes in serum sodium and calcium or body weight changes [ 72].

Although mechanistic details are still missing on how activation of cell death pathways is linked to mitosis duration, prolongation of mitosis appears crucial for the ability of antimicrotubule cancer drugs (AMCDs) to kill cancer cells.

We find that simulation of action potential duration prolongation, at therapeutic concentrations, provides improved prediction of the TdP risk associated with a compound, above that provided by existing markers.

Finally, the use of n-3 polyunsaturated fatty acids in the sterile pericarditis model was associated with lower levels of inflammatory markers, a reduction in AF inducibility and AF duration, prolongation of the refractory period, and shortening of intra-atrial conduction times.

As expected, application of IKur blocker produced pronounced action potential duration (APD) prolongation in atrial myocytes.

Beat regularity and duration (QT prolongation or shortening) can also be affected, which can lead to polymorphic ventricular tachyarrhythmia, seizures and sudden death.

The intracellular recording revealed a marked increase in action potential duration (APD) prolongation, and an increase in the degree of variability in HCM iPSC-CMs compared with control iPSC-CMs (CTL, n = 23; HCM, n = 41).

Cardiomyocytes (CMs) differentiated from these two pairs of isogenic hPSCs demonstrated that the N996I KCNH2 mutation causes an ∼30 40% IKr reduction with consequential action potential (AP) duration (APD) prolongation, and indicated a trafficking defect as the associated pathological mechanism responsible for the disease electrophysiological phenotype.

Prolongation of session duration may prolong the unfavorable hemodynamic changes that occur during hemodialysis, thus negatively effecting myocardial perfusion.

Prolongation duration of brain death beyond 10 hours in DD resulted in a significantly decreased CASP3 expression in biopsy 1.