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Capecitabine-attributed ST was diagnosed after median treatment duration of three cycles.
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Patients with s.d. had a median duration of five cycles.
This investigation with ten debris insertions spaced over a duration of five million cycles demonstrated consistent trends of wear (linear-regression coefficients R > 0.98) that indicated the methodology was applicable for future scientific study.
The duration of one cycle was 1000 ms. During the both pre-test and test phases, infants were presented with 10 cycles on each trial.
A total of 46% of the evaluable patients had SD as their best response, with a median duration of treatment of three cycles.
This high incidence of grade 1/2 non-haematological toxicities may be associated with the long treatment duration, a median of eight cycles per patient.
The expected duration of treatment must be at least of eight cycles (4 months; for details see box 1).
For each scenario, 500 patients were simulated for a duration of seven treatment cycles (i.e., 147 days), unless patients would dropout earlier.
The 66 platinum-sensitive patients received 304 cycles with a median of four cycles per patient (range, 1 11); median treatment duration was 18.6.
Each of the two test runs consisted of six cycles of circular movement corresponding to 15 s in duration per test run.
The half-life of the GFP protein in cycloheximide-treated cells undergoing metabolic cycles was ∼4.5 hours (Figure S2), which is approximately the duration of one complete cycle in our culturing conditions.
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