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Main outcome measures Duration of injecting: years from first injection to long term cessation, defined as last injection before period of five years of non-injecting; mortality before cessation; overall survival.
Analysis was adjusted for marital status, educational level, duration of injecting, sharing needles or syringes, and injections by a nonmedical provider.
Treatment does not reduce the overall duration of injecting.
Recruitment setting and duration of injecting drug history were forced into all models to avoid potential confounding.
The factors most closely associated with HCV infection are duration of injecting drug use and HIV-1 co-infection.
Site-specific unbiased estimates of the average duration of injecting until cessation are unavailable and difficult to obtain.
Similar(30)
At higher exit rates (ie, in populations with shorter durations of injecting) scaling up OST and HCNSP achieves more impact than at lower exit rates, whereas the opposite occurs for scaling up antiviral treatment, but less so (Supplementary Figure 4 A and B).
The performance characteristics of the PET scanner, scan timing and duration, measurement of injected activity and a number of other technical factors can all affect precision and accuracy of quantitative measurements.
Equally, people who start injecting at an older age (after 25 years) may have greater comorbidity and/or other risks, such as homelessness and prison history, that increase their HCV risk, or there may be a greater misclassification of injecting duration among older injectors.
The results indicate that time delay and pulse broadening depend on the shape, energy and duration of the injected pulses.
Characteristics of injection drug use practice (longer duration of injection drug use, main drug injected), correlates of high-risk injection behaviour (higher injecting frequency, sharing), and problem alcohol use were associated with the risk of overdose within the previous 12 months.
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