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The age of onset of the bipolar group (14.9 ± 3.5) was significantly less than that of the psychosis group (17.7 ± 4.3; t(111) = −3.81, p < 0.001), though the duration of illness between groups did not significantly differ (psychosis group 5.8 ± 3.5 years; bipolar group 7.1 ± 3.9 years; t(111) = 1.67, p = 0.097).
There was no significant difference in duration of illness between the two codon 129 genotype groups.
All of the episodes, except two, were very similar in their clinical course, with the duration of illness between 4 and 15 weeks (median, 7 weeks).
There were no significant differences in sex, mean age at onset, mean onset of illness or mean duration of illness between the MCI and AD groups, or between men and women in general.
ANOVA comparison of age at onset, death and duration of illness between C9ORF72 associated FTD, FTD + MND and MND groups alone revealed no significant group differences in age at onset (F2,17 = 0.77, p = 0.477) or duration of illness (F2,17 = 1.4, p = 0.227), though duration of illness tended to differ between the 3 groups (F2,18 = 4.1, p = 0.045).
However, there were no significant differences in duration of illness between C9ORF72 associated FTD, non-mutational FTD or GRN associated FTD (F2,37 = 1.6, p = 0.215), or between C9ORF72 associated FTD + MND and non-mutational FTD + MND (p = 0.900), or between C9ORF72 associated MND and non-mutational MND (p = 0.605).
Similar(51)
This unexplained heterogeneity means that the effect size (i.e. the difference in the duration of illness episodes between treated and untreated individuals) may differ between the population groups.
The age range of the patients was between 55 to 81 years at death and the duration of illness varied between 2 and 12 months (Table 1).
Duration of illness was between 4 to 7 days in 61.7% of troops reporting an illness.
For children with seasonal influenza neuraminidase inhibitors seem to have a small effect in terms of reducing duration of illness of between 0.5 and 1.5 days.
Duration of illness varied between 0 (first admission) and 22 years around a mean of 5.78 ± 5.8 years, and did not differ between male (5.40 ± 5.9) and female patients (7.5 ± 5.3; t(63) = 1.13, p =.26).
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