Sentence examples for duration of dosing from inspiring English sources
The differences between the reactions of the primates and human subjects has also to do with the differences in the amount of prGCD given and the frequency and duration of dosing (up to 27.8 mg/ml for 9 months in primates and only up to 1.8 mg/ml in humans over a 4 week period).
There was no evidence of a dosage effect or an association to the duration of dosing at the onset of the event.
The DAS28-ESR and ACR scores reported for adalimumab in the DMARD-IR population in this study are comparable to historical values for this duration of dosing [ 25- 27].
In addition, dose intensity for the treatment period was calculated as the total cumulative dose divided by the duration of dosing (i.e. [start date of last cycle] – [start date of first cycle] + 14).
The flow rate, duration of dosing, dose solution concentration were optimized and adjusted according to the dosage required.
3) Either the dose, dosing schedule, or duration of dosing is suboptimal.
The same approach has been applied to thyroid cancer patients treated with motasenib [ 26, 65] where the probability and duration of dose reduction and interruption were also modelled.
The median duration of dose interruptions/reductions was higher with EVE (11 days) than with PBO (1 day) or EXE (1 2 days) (Table 3).
The duration of dose interruptions/reductions was relatively short, and most patients who resumed the full 10 mg EVE dose did so within 2 weeks, thereby maintaining dose intensity.
Twenty-seven patients (48.2 %) had ≥1 dose delay; for any reason; the duration of dose delays was typically <2 weeks (18 of 27 patients), with a median of 50 days (range 1 217).
