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t R duration of compound release in the supernatant (min).
The data presented in this study illustrate the complex effects of HSP90 inhibition on cell division: Cell cycle perturbation profiles were dependent on the concentration of HSP90 inhibitor, cell line genotype, and the duration of compound treatment.
The exact duration of compound treatment prior to application of the MMP detection dye will likely have an effect on the activity assignments mentioned above.
Transgenic larvae were treated from 3 to 5 dpf with compounds across an expanded concentration range (0.5 25 μM) to account for differences with the primary assay (e.g., transgenic line used, timing and duration of compound treatment) and/or differences between compound lots.
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In this and all subsequent experiments the intertrial interval (ITI) was of a mean duration of 75 s (range 60 90 s), and all stimuli were of 10 s duration; on compound trials a 5-s trace interval separated occasion setter offset and target CS onset.
The duration of a compound load process reflecting daily activities lasted 240 min.
No differences were present in latency and duration of the compound action muscle potential between septic and control animals.
An approximate six to nine fold increase in γ-H2AX resulted from treatment with 250nM AF in Cal51 for the duration of the compound treatment, but presence of PARP cleavage was not evident.
Open image in new window Fig. 2 Method of treatment Open image in new window Fig. 3 a. 35-year-old male with infected non-union of Tibia of 11-year duration following compound fracture of both bone leg.
It was previously reported that repetitive activity resulted in changes in the magnitude, duration, and repolarization rate of compound action potentials (CAPs) in peripheral nerve tissue [7].
The duration of POP inhibition of compounds was evidently not governed by their serum clearance.
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