Sentence examples for duration of action potential from inspiring English sources

Inserting such channels into cellular and network models results in changes in the excitability of the cells (e.g., the duration of action potential, and the frequency of spiking) [8, 9].

In our unpublished data, we found that U50488 could shorten the duration of action potential and decrease the contractile force in guinea pig left atrial preparations.

Ito is a major repolarizing K+ current in ventricular myocytes, which contributes to the early phase of repolarization, influencing the shape and duration of action potential.

Both extracellular and cytosolic magnesium has significant effects on cardiac ion channels, which in turn may have important consequences on the duration of action potential, cell excitability and contractility [ 130].

These experiments suggested that reducing the level of DISC1 by ˜60% may serve to increase the duration of action potential bursts, although whether this reflects an intrinsic or synaptic change is not apparent from this type of data.

However, BaCl2-evoked astrocyte depolarization did not affect the duration of action potentials during barrage firing (Fig. 2e).

The rationale for not using 100 µM Alexa Fluor 488 [14] to guide the connection between the soma and axon is because we found that Alexa Fluor 488 broadens the duration of action potentials and reduces the amplitudes of sequential spikes.

Presynaptically, μ-opioid receptor activation diminishes Ca2+-dependent,exocytotic neurotransmitter release by inhibiting voltage-dependent Ca2+channels, or by activating K+ channels, which raises the threshold and shortens the duration of action potentials [29], [30].

Detailed analysis of action potential signals in this muscle indicates that the duration of action potentials measured at 50% of repolarization time (APD50) with a big Ca2+ release (148±1.9 ms, n = 7) was ∼20% shorter than that with a lesser Ca2+ release (188±4 ms, n = 6).

These cells showed disease-specific anomalies in the duration of action potentials, the action potential rate adaptation and IKs currents.

GIRK channels play an important role in maintaining resting membrane potential and regulating the duration of action potentials (Hille 1992).