Our observation that the structural and functional disturbances of the extrasarcomeric cytoskeleton led to an increased susceptibility of muscle fibers to mechanical strain implicates that in patients with desminopathies physical activity beyond a certain threshold or duration might aggravate the skeletal or cardiac disease progression.
In addition, it is found that the introduction of the self-calibrating procedure for duration factors further aggravates the dependence of drought index on input datasets compared with original empirical algorithm that Palmer uses, making SC-PDSI more sensitive to variations in data sample.
The duration, inducing (or aggravating) factors and relieving factors of chest pain are the main factors to determine the feature of CHD.
Forty-five female volunteers aged between 18 and 40 years with a history of insidious onset of pain located between the knee and ankle of at least one month duration that is aggravated by weight bearing activities will be recruited for the study.
This proved, however, to be of short duration, for affairs in Armenia, aggravated by Roman operations on Parthian territory, had brought the two empires to a parting of the ways.
The blocking index number, an index of nasal swelling, was aggravated with exposure duration, but no exposure-response association was found, showing that MTBE was not the decisive factor for this symptom.
On the other hand, we do not exclude the possibility that high dose of OPLE, depending on the duration of treatment, may perhaps aggravate oxidative stress in our animal model of DN.
Furthermore, the high-frequency EA stimulation aggravated the amplitude and duration of the epileptic EEG activity induced by pilocarpine.
Short duration between the onset of labor and delivery aggravated this situation.
The SLPQRW score was also reduced in patients with long disease duration, probably because headache and especially migraine persistence may aggravate this aspect of sleep.
