Evidence from concordant insertions of repetitive elements strongly supports the interaction of the J-J-C regions in driving the sequence of duplicative events.
Various models of genomic duplications, e.g. the duplicative transposition or the endoduplication, have been documented.
Duplicated pseudogenes are often distributed in the flanking of the parent genes and may still maintain the upstream regulatory sequences of their parents due to their duplicative origin.
More recently, the role of duplicative transposition – the copying and pasting of particular DNA sequences from one part of genome to another – has been shown to play an important role in the evolution of new genes (e.g. [ 3]).
In contrast to duplicative transpositions, endoduplications originate from tandem duplication events of local chromosomal regions mediated by unequal crossover.
Often these duplicative origins were accompanied by conversion or rapid divergence of gene sequences, and experimental evidence elsewhere suggested that the novelty created by duplication is maintained to satisfy the requirements of particular life stages or for precise regulation of specific amino acids.
UVPD, on average, produced more than 95 fragment ions per protein identification; however, a large proportion of the ion current resided in a- and x-type ions, which are sometimes duplicative for the same inter-residue position in the protein sequence.
Removing redundancy from contigs of A. thaliana was tested using non-duplicative or duplicative combined protein database (PlantClust50 DB or Plant DB, respectively), which consisted of protein sequences of 14 species of plants.
Amplification of a satellite sequence is reported to occur as a result of unequal crossing over or duplicative transposition (Smith 1976; Ma and Jackson 2006).
However, the duplicative nature of teleost genomes, including the zebrafish, complicates accurate assembly and annotation of a representative genome sequence.
