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The high homology between different zones of the IGH locus (as exons as introns) indicates recent duplications processes.
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Consequently, little information is available over short time-frames on the dynamics of duplication processes, including the divergence of duplicated copies.
Mammalian genomes have a large number of duplicated genes due to different gene or genome duplication processes [ 42].
The modeling of switching systems describing networks where death and duplication processes occur is described.
Second, a search was performed for retroelements that may have played a role in duplication processes as observed in the macaque B region.
Subsequent to the duplication processes, recombination between MIB and Mamu-B loci appears to have occurred, resulting in a hyperplastic B region.
For these reasons, we intended to screen for such retroelements and for their potential implications in the functional and evolutionary genomics of the duplication processes within the class I B region of rhesus macaques.
It seems plausible that subsequent to the duplication processes, recombination has occurred between various MIB and Mamu-B loci, promoted by associated transposable elements acting as recombination hotspots [30] [36], resulting in a hyperplastic B region.
Bacterial evolution experiments [ 15] provide opportunities to identify intermediates during duplication processes.
Furthermore, all plant genomes have paralogous regions arising from gene duplication processes other than allotetraploidization (such as tandem duplication).
Note that both whole chromosome and tandem duplications give rise to topohomology, as they are both symmetric duplication processes.
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