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We explore the abilities to examine differential expression, gene duplication, transcript assembly, alternative splicing and SNP discovery.
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We defined a pseudogene as a duplicated transcript that has lost its original function due to incomplete duplication or at least one interruption of the ORF.
Instead, biological factors involving gene duplication or transcript processing may complicate the unambiguous assignment of signatures to transcripts.
Filamin C (FLNC) appears to be a true duplication, with transcripts divergent at the nucleotide and protein levels.
In both families tested, this chromosome 12 duplication and associated transcript were present in the probands' affected sibling, as well as an unaffected brother in family 3044.
Most of the existing plant genome browsers provide conventional data on gene models, transcripts, duplication, syntenic regions and repetitive elements.
PCR from genomic DNA or single-stranded cDNA was used to detect duplication events or transcripts corresponding to the locus, respectively.
In some cases, these MIRNA loci formed through inverted duplication events that yielded transcripts with self-complementary foldback structure [22].
We find that the majority of transcripts of duplication peptides have exons that align to a single unique macaque alignment net (66%).
Users can use these tabular results to guide decisions about which loci to pursue for downstream marker development or to investigate further the duplication status of secondary transcripts for particular genes of interest.
Despite these various processes that could account for the evolution of toxin diversity, it has never been demonstrated how gene duplications or variations in transcript or peptide processing could have radiated across the very different poisonous creatures found on Earth.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com