Sentence examples for duplication subject from inspiring English sources

Because of its mosaic nature, duplication subject 3 should be indicated on Figure 2. We have labeled the mosaic patient on the figures.

Because of its mosaic nature, duplication subject 3 should be indicated on Figure 2. The relationship of high and low NUDT21 expression in GBM tumors has already been shown to result in shifts in abundance of long and short MECP2 transcripts presumably as a result of preferential PA site usage (see Figure 4, Masamha et al., 2014).

We also observed that 15q duplication subjects have mild facial anomalies.

We must also note that two out of four paternal duplication subjects examined also had autism (Table  1).

DOI: http://dx.doi.org/10.7554/eLife.10782.008 10.7554/eLiFigure82.009 Figure 3 figure supplement 2. Polyribosome fractionation traces of control and duplication subjects.

An advantage of this method is that parental DNA is not required, so it can be run on all 15q duplication subjects, even if they were adopted.

The ascertainment bias in the collection of paternal duplication subjects and the small number of subjects with paternal duplication that were analyzed makes it impossible to conclusively establish that paternal duplications of 15q do or do not increase autism risk.

Here we have shown for the first time that maternally derived or inherited duplications of the region between BP2 and BP3 are sufficient to produce a phenotype on the autism spectrum in all nine maternal duplication subjects tested.

(C ) Western blot and its relative quantification showing that knockdown of NUDT21 by siRNA- NUDT21 nucleofection increases MeCP2 in control and duplication subjects, and normalizing CFIm25 in duplication patients rescue MeCP2 to control levels.

A recent study revealed that maternally derived or inherited duplications of the region between BP2 and BP3 were sufficient to produce a phenotype on the autism spectrum in all nine maternal duplication subjects tested [ 20].

A limitation in this study is the lack of sufficient power for meaningful statistical comparisons between maternal and paternal duplication subjects due to a small number of paternal int dup(15) subjects.