Your English writing platform
Discover LudwigExact(6)
This is a further hint towards a tandem duplication random deletion event, although there are no apparent sequence homologies to any of the lost genes.
The tandem duplication random deletion model was proposed when more than one gene was involved and/or non-coding sequence was found between the genes involved.
Three different modes leading to a change in gene order were assumed: (1) tandem duplication random deletion events [ 52], (2) inversions, and (3) transposition of single tRNAs.
Metastriata (Parasitiformes: Ixodidae) show a derived gene order probably caused by a tandem duplication random deletion event and an additional tRNA translocation (Rhipicephalus [ 42], Haemaphysalis [ 53], Amblyomma, [GenBank: NC_005963]).
Thus, the most parsimonious and simplest explanation is that the evolutionary pathway that generated the antGOs started from PanGO, and through three successive rounds of duplication random loss events, ended in ant3GO (fig. 3).
Lastly, apply tandem duplication "random loss" (TDRL) to the C. azureus mitogenome, the "loss" events, from the duplicated genome to the C. azureus type, shared very peculiar characteristic: only the L-strand coding gene including ND6 and tRNA of P, E, S, Y, C, A and Q was translocated and grouped together.
Similar(54)
The loss of a gene segment reported by Yu et al. (2008) was an artifact due to placing PCR primers in a duplicated gene, and the phenomenon of "tandem duplication-random loss" does not exist in the mt genome of C. hongkongensis.
Gene rearrangements are commonly explained by a process of "tandem duplication-random gene loss" [ 40], assuming that duplicated portions of the mtDNA can be generated by several processes, and that supernumerary copies of each gene will be selected at random to be subsequently eliminated [ 41].
The extensive reorganization of NC regions could partially be related to the extensive changes in gene order, indeed a process of "duplication-random gene loss" can generate NC fossil sequences, as remnants of duplicated genes erased by evolution.
This is very likely an example of "tandem duplication-random loss (TDRL)" mechanism for gene rearrangement.
The tandem duplication-random loss model has been invoked to explain the mechanisms of most mitochondrial gene rearrangements.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com