Sentence examples for duplication lines from inspiring English sources

The map of all genes along the 10 chromosomes and duplication lines among genes were drawn manually.

All this together, along with the rescue experiment in the duplication lines, supports our conclusion that NUDT21 alters MeCP2 levels, and, hence, is the driver of pathogenicity.

When differentiated to neurons, lines from one individual consistently developed phenotypes similar to those observed in the familial AD (APP duplication) lines: increased Aβ40 production, tau phosphorylation and an increase in the number of large early endosomes.

Our gene expression findings are consistent with other studies in mouse deficiency and duplication lines where the expression of the large majority of genes reflected DNA copy number (Kahlem et al, 2004; Li et al, 2009; Pereira et al, 2009; Prescott et al, 2005).

Following the railway grouping of 1923, both the South Eastern Railway and the London, Chatham & Dover Railway became part of the newly formed Southern Railway, which decided to address the duplication of lines and stations at Ramsgate and Margate.

Both compounds inhibit JAK-signal transducer and activator of transcription (STAT) signaling in AML cells with JAK2V617F mutations, but also diminish FLT3 signaling, particularly in FLT3-ITD (internal tandem duplication) cell lines.

In the first tier screen, we developed and applied an unbiased phenotyping screen focusing on five therapeutic areas (metabolic syndrome, immune dysfunction, atherosclerosis, cancer, and behaviour) to identify gene dose-dependent phenotypic changes in reciprocal 0.8 Mb deficiency (Df11[1]/+) and duplication (Dp11[1]/+) lines on chromosome 11 containing 27 genes (Liu et al, 1998).

The results of such analyses, however, did not provide support for the enrichment of either segmental duplications or LINEs, nor did it reveal any overlap of segmental duplications in the 500 bp flanking sequences.

The F' plasmid is positioned according to its 3D contacts with the E. coli genome, without taking into account the duplication (dotted line within the E. coli genome).

Finally, this group also observed an increase in the number of large early, Rab5-positive endosomes in neurons generated from an APP duplication iPSC line, consistent with the findings from the Abeliovich group.

These include constraints concerning line elements, duplication, connectedness, inclusiveness, closure, good figures, and line sharing.