Sentence examples for duplication control from inspiring English sources

To test whether the unusual evolutionary and expression properties of nested genes are due to the larger proportion of duplicate genes, we compared nested genes with a set of control genes that have the same proportion of young duplicated genes ("duplication control genes," see Materials and Methods).

In addition to further tease apart the main evolutionary force that might have led to some of our observations, we generated additional control gene sets that match either the proportion of DNA/RNA-duplicated genes of nested genes (duplication control genes) or gene expression of nested and including genes (expression control genes).

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We propose a general model for centriole duplication control in which cooperative binding of duplication factors defines a centriole 'origin of duplication' that initiates duplication, and passage through mitosis effects changes that license the centriole for a new round of duplication in the next cell cycle.

Immunofluorescence microscopy confirmed this result and also revealed signs of overduplication, indicating a failure of proper duplication control.

Duplication control genes were matched to have the same proportions of DNA and RNA duplicate genes and chromosomal distributions as nested genes.

Having identified carriers of the duplication in control cohorts, we were interested in testing whether 'control' individuals had psychiatric or developmental phenotypes.

CEP63 is localised to the centrosome in eukaryotic cells and is required for maintaining normal centriole duplication and control of cell cycle progression.

For instance, Cln1/Cdc28 and Cln2/Cdc28 function in budding generation and spindle pole body duplication; Cln3/Cdc28 controls the size of newly formed cells (Chen et al., 2000).

Yet to date there is little information on the genomic role of gene duplication in controlling intraspecific genetic variation in gene expression or other traits.

Conserved, flanking collinear homologous gene pairs between the two genomic regions were searched for microsynteny to determine the segmental duplication events, controlled by a statistical distance function [ 23].