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In addition, gene duplication around Glo1 was observed in several mouse strains (Egan et al. 2007; Williams et al. 2009).
We then investigated the colocalization of Plk4 with STIL at the onset of centriole duplication around the G1/S phase transition.
Our results indicate that the euAGL6 and AGL6-like sequences were likely retained early after a genome duplication around the origin of the core eudicots.
There is evidence for an ancient duplication around the bilaterian origin; however, the testis-specific copy was found only in vertebrates, which makes this scenario rather unlikely.
Teleost fish underwent whole-genome duplication around 450 Ma followed by diploidization and loss of 80 85% of the duplicated genes.
The first one is likely to represent random sequence matches, while the second one is indicative of transposable elements (Lam et al., 2010), characterized by Target Site Duplication around breakpoints (∼15 nt in length).
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In contrast, recent gene duplications, those duplicated around the mammalian radiation or in the rodent lineage, are expected to have significant contributions to the gene robustness in the current mouse genome.
Twenty-seven gene families neighboring the opioid peptide genes present phylogenetic topologies and species distributions that are consistent with duplications around the time of 2R.
Recent genome-wide association studies (GWAS) of schizophrenia identified rare de novo copy number variation (CNV) [7] and an increased load of micro-deletions and micro-duplications around coding regions [8], [9].
The Arabidopsis genome appears to have undergone ancient genome duplications around this time window [ 21, 22].
Genome duplications around the time window of 50 mya were also reported in other flowering plants including grasses and Solanaceae plants [ 23].
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