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After the removal of duplicates through electronic databases, 634 studies remained.
Yet, as shown in this work, the retention of gene duplicates through subfunctionalization must also encompass adaptive elements.
We go on to describe experimental works that shed light on the fates of duplicates through classical events (such as neofunctionalization and subfunctionalization).
Tb32 (75 kDa invariant surface glycoprotein) included a divergent copy at its 5' end that differed from other duplicates through frequent indels.
Concerted evolution will homogenise tandem gene duplicates through unequal crossing-over between sister chromatids or chromosomes, or through allelic gene conversion.
In neofunctionalization, related or novel function may arise in one of the duplicates through initial relaxation of purifying selection with accumulation of mutations conferring new function under either neutral or positive selection.
Similar(54)
Genes can be duplicated through tandem duplication and retrotransposition.
The founder of the array of F3'5'Hs on chr6 was initially duplicated through tandem gene duplication.
Genes are duplicated through two main duplication mechanisms; DNA-mediated and RNA-mediated [ 27, 28].
From this initial chromosome organization, the ancestral diploid genome was duplicated through Whole-Genome Duplication (WGD) then fragmented giving rise to an intermediate ancestor with 2n = 2× = 24 chromosomes [ 11].
Trans-NATs expressed antisense of pseudogenes can be duplicated through events of genomic duplication.
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