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Exact(13)
Overall, tandem duplicates did not show a significantly higher frequency of asymmetric rate evolution than WG duplicates (χ, P = 0.9317).
Sera were rescreened if the duplicates did not agree based on a similarity measure between them (see Supplementary Methods).
The other duplicates did not affect the physician and nurse groups since they had chosen both "cardiology/heart" and "other", but stayed within the group of physician/nurse.
The values for two β-CA genes from Setaria were averaged because these duplicates did not differ in their coding sequence.
Results were regarded as valid if both duplicates were in the same category (both positive and negative) and duplicates did not differ by more than 20%%.
Of these 52 samples at 345 SNPs, the genotypes of 23 duplicates did not match each other and 19 data points were missing, giving a discordance rate (error rate) of 0.26% (23 of 8,951 data points).
Similar(47)
Hence, the probability of a gene duplication or retention of gene duplicates does not appear to differ between the autosomes.
This indicates that an overrepresentation of edges between proteins of a similar age, due to conservation of ancestral interactions in both duplicates, does not arise automatically from a process of network growth by node duplication such as we modeled here.
Lewis agrees that recombinations of this-world duplicates do not suffice to "generate" alien possibilities.
Thus, constructing a -net by picking points independently at random (with duplicates) does not lead to correct analysis.
This way of constructing a -net may result in duplicate points in, but the presence of duplicates does not cause a problem in the analysis.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com