In addition, expression correlation between gene pairs was generally two-fold higher in recent duplicates than in single duplication events.
The higher number of tandem duplicates than retrogenes in both genomes implies a higher gene duplicability for tandem duplicates.
We find a pattern of increased gene duplication in these Lake Malawi haplochromines, with 38-49% more genes duplicated than in the non-radiated lineage.
It has been suggested that broadly functional genes are more easily duplicated than functionally established ones, and that the modifications that follow the duplications should provide the appearance of new functional specificities.
Another alternative is that tandem duplicate genes supposedly arise from more recent events of gene duplication than dispersed duplicate genes.
A buffered data frame will be discarded when more duplicates than the threshold are received subsequently.
Nevertheless, as shown above, the rate of relocalization is not significantly higher in duplicates than in singletons.
Interestingly, the latter group of genes tends to be more anciently duplicated than the former group of genes.
Instances where divergence was significantly greater between some duplicates than others are referred to as having 'mixed dynamics'.
For example, the effect of gene conversion, which keeps duplicates appearing similar through local DNA recombination [ 28], may have greater influence on tandem duplicates than retrogenes.
