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I once watched him rehearse a scene in the film "Duplicate," in which he had to stab the picture of his enemies with a knife, repeatedly, in great anger.
To assess the false-positive rate of our analysis procedure we first performed a control experiment, in duplicate, in which both samples were incubated with an affinity matrix loaded with the immunophilin-modulating compound AP-1497, but no soluble competitor was added.
The other copy resulted in a tandem gene duplicate in which the new copy was placed at the 5' site of the original gene (2A).
The recurrence for is the same as for d i in Eq. 3. In the latter case, we consider an inverted duplicate in which y1 is generated by - x i.
Similar(56)
Some studied species might retain both duplicates, in which case the gene will not be a one-to-one ortholog, and thus should be recognized and discarded.
Following removal of duplicates in which the same fragment had been cloned more than once (in the same vector or between several vectors), 168 unique probes were accepted.
We found 14,551 references from 9 databases, and 11,754 were left after deleting duplicates, in which 1,106 were evaluation studies about interventions to improve maternal and child health.
After the inference of the MRCA expression pattern between extant duplicated gene pairs, we tested for asymmetric protein sequence evolution for these reciprocally expressed gene duplicates, in which one copy has accumulated more amino acid mutations than the other copy after duplication.
These patterns are consistent with models of gene duplicate divergence in which a gene duplicate assumes a portion of the function and/or expression of a progenitor gene having broad function and/or expression.
Intrachromosomal duplications in which the duplicate is inserted in the reverse direction (inverted duplication) are likely to be a major source of false positives for this analysis.
Instead, they largely result from simple exact duplicate matching, in which once a human moderator deletes a piece of content, it is added to a site-wide blacklist that prevents other users from reuploading it.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com