Sentence examples for duplex separation from inspiring English sources

In contrast, the lagging strand synthesis is initiated from a separate single-stranded origin, which only becomes available once the duplex separation has gone past this origin (12).

Leading strand synthesis is unidirectional from ori and follows the duplex separation around the plasmid.

This system has previously been shown to provide sufficient signal to measure duplex separation (27).

The ATP enables PcrA to start duplex separation, and the SSB then binds to the resultant ssDNA strands.

This requires duplex separation to occur on one side of the helicase prior it reaching the hole.

We have identified two aromatic residues near the FeS cluster that may serve as a wedge for initiating duplex separation.

These observations support involvement of G4 DNA in recombination, predicting a functional model that is consistent with duplex-strand separation induced by formation of G4 motifs in supercoiled DNA and/or when assisted by other cellular factors.

Since the formation of triplex DNA implies a sharp bend in the DNA molecule, these observations predict a functional model that is consistent with a duplex-strand separation mediated by the TCC-repeat motif that does not end in recombination or chromosome break but fold back the DNA initiating a loop configuration that brings together both targets.

TacXPD contains two aromatic residues Y130 and F131 poised to base stack with DNA from the duplex as strand separation occurs.

We first verified that PICH indeed did not catalyse strand separation of duplex DNA in a classical helicase assay.

The SNF2 family of helicases is typically involved in chromatin remodelling by translocating on DNA and does not generally catalyse strand separation of duplex DNA.