McNeil et al. [ 27] found older people to be more fatigable than young during a velocity-dependent power task and suggest their contrasting findings are due to the more functionally relevant task, which employed a lighter load, and is more comparable to daily life tasks.
Due to the existence of functionally redundant parts, a system may exhibit no or only mild phenotypic changes upon malfunction of a part.
As the repair of UV damage is, at least in part, dependent on the p53 status of the cells (Ford and Hanawalt, 1995, 1997), the failure to repair DNA damage effectively may be due to the cells being functionally p53 null.
The trends observed are generally much lower than observed for superfamilies (see Fig. 6 and Supplementary material Fig. A.16) supporting the idea that the higher site coverage observed when the whole superfamily is considered is largely due to the fact that functionally different relatives are exploiting different sites on the domain for binding ligand/protein partners.
The high sequence conservation of the cytoplasmic tail (Table 2) is mainly due to the presence of the functionally critical ITAM found in this region (Fig. 2).
This was mainly due to the fact that although the functionally equivalent DC subsets shared several phenotypic features with their counterparts in lymphoid tissues, they did not, in fact, express CD8.
Due to the conformationally independent but functionally coupled populations, the overall activity is given by the linear superposition/weighted mean of both activities where k u and k s represent the contributions of unstimulated (A u ) and stimulated (A s ) transducers due to different expression levels.
In this work, with the assumption that the oral cancers were caused due to the dysfunction of multiple functionally related genes [ 42], we proposed a novel pipeline to identify gene modules that play important roles in the development of oral cancers.
Due to the extensive sequence identity between the functionally different SlAAAD and AtSDC enzymes, it was presumed that these enzymes might share some overlap in substrate specificity.
In addition, the transfection of chemically modified CFTR mRNA in mutated CFBE41o− cells restored cAMP-induced CFTR currents similar to wild type cells due to the mRNA-driven replacement of functionally active channels [20].
