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In most organisms, aging might be due to random mutations in individual cells.
The word is now used in an almost totally different sense, which has got to do with changes in the DNA that are not due to random mutations.
Variability within these sequences is not due to random mutations within one consensus sequence but to two or more well-defined consensus sequences.
Local alignment analysis of these variable blocks revealed that their variability is not due to random mutations on a single consensus sequence.
We cannot exclude that some of nucleotide substitutions in mtAncestor-1 and mtAncestor-2 were due to random mutations that occurred after integration of these loci into the nuclear genome.
Moreover, since different members of a family of repeated DNA elements are usually not identical due to random mutations, one repeated element might have an FRT-like sequence but another might not.
Similar(48)
A central tenet of evolution is that unnecessary genes become non-functional due to random mutation.
Right after amplification, copies are almost identical but will diverge in sequence and length over time due to random mutation.
After a polyploidy event, redundant duplicated genes will be lost from the genome due to random mutation and loss of function.
It is widely accepted that redundant duplicated genes will be lost from the genome due to random mutation and loss of function, except when neo-or sub-functionalization occur [ 60, 61].
As there is no rule without exception, we found that genome dosage-sensitive call patterns can be interrupted in certain populations, possibly due to random mutation, introgression or local selective forces.
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