Exact(11)
Alpha was decreased to 0.01 due to multiple tests.
Multivariate analysis also protects against inflated type I error due to multiple tests, especially when DVs are correlated (which was the case here).
To cope with the multiplicity effect, that is, the chances of getting an increased number of significant results due to multiple tests, we adjusted the values as described in [34].
Due to multiple tests, it is even likely that these effects are, in reality, not significant.
To address the issue of false-positivity due to multiple tests, a permutation test [ 17] was performed when needed.
We used this adjustment to prevent the overall error rate from exceeding the nominal criterion (alpha) due to multiple tests.
Similar(48)
The use of full Bayesian statistics can account for problems of multiplicity due to multiple testing [ 24, 40, 41].
In this type of studies the significance level is very difficult to achieve (5 × 10− 8) due to multiple testing.
Due to multiple testing, we set the threshold of the HWE test at P = 0.001.
Furthermore, we have assessed 9 predefined possible associations, giving rise to the possibility of random error due to multiple testing.
The study examined association with many risk factors, and some of the reported findings may therefore be spurious due to multiple testing.
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