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Several evidences depict that the expressions of miRNAs are remarkably modulated in malignant tissues due to multiple genomic and epigenetic alterations.
Third, increasing evidence shows that the expression of miRNAs is remarkably deregulated in cancer due to multiple epigenetic and genomic alterations.
He died of anaphylactic shock due to multiple beestings.
This could be due to multiple mechanisms.
‡Adds to >100% due to multiple exposures.
Widespread microcirculatory abnormalities and cellular alterations leading to an uncoupling between blood flow and metabolic tissue requirements, particularly in splanchnic perfusion, are common in septic patients and have been implicated in sepsis-related mortality due to multiple organ dysfunction [ 1- 3].
The one area that has gone in favor of the teams in future guaranteed salaries, as the Chiefs were able to get out from under future obligations to Larry Johnson due to his multiple nightclub altercations a year ago.
It has been postulated that the mechanism of malformation and overgrowth during embryogenesis is due to the alteration of multiple signalling pathways including the insulin-like growth factor, vascular endothelial growth factor, and fibroblast growth factor pathways [ 84].
In this model, the key molecular event is the inactivation of multiple tumour suppressor genes (TSGs) due to genetic alterations.
Structural alterations due to mutations cause alterations in ligand escape.
We then investigate, using flow and transport modeling on a heterogeneous field, the relationship between percent zeolitic alteration, permeability changes due to alteration, sorption due to alteration, and their overall effect on radionuclide transport.
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