Sentence examples for due to internalization from inspiring English sources

We have shown, however, that there is a large difference in residence time of the PET imaging signal, likely due to internalization and subsequent residualization of the 89Zr label versus rapid efflux of the 124I label.

Therefore, the upper limit to the decrease in net BRET one could expect due to internalization is within this range.

Note that VEGF levels are depleted to ∼0.988 pM at the tip cell due to internalization from the 104 VEGFR2/cell along the sprout length (Fig. 2C).

It is therefore possible that at high levels of CCL20, the chemokine receptor CCR6 is desensitized due to internalization and/or phosphorylation [25].

We next determined if anti-Ig mediated downmodulation of gp41 MPER binding was due to internalization of gp41 MPER/Ig complexes by pre-incubating with anti-Ig Abs (Fig. 4E).

For example, if half of the total BRET signal originated from intracellular compartments prior to agonist stimulation, then only 25% of the total BRET signal could be lost due to internalization of 50% of the receptors originally present on the plasma membrane.

The structure appeared within 12 h, and further incubation resulted in its growth into a large cellular aggregate due to reiterative internalization, which hampered the accurate enumeration of internalization ratio after 24 h.

In case efficiencies are present, it is possible to disentangle the effect of the increase in prices due to the internalization of competition between the merging firms and the effect of the synergies.

This result confirmed that the antibacterial activity also depended on the size, and it was probably due to the internalization and subsequent accumulation of NPs inside the cells until the particles reached the cytoplasmic region.

However, the effect seen in vivo could nevertheless in part be due to some internalization of the 111In-Fab by the tumour cells as the cellular membrane renews itself, even though our in vitro experiments showed no detectable internalization of 111In-Fab into either H314 or A431 tumour cells up to 24 h of incubation at 37°C.

However, several studies suggest that the correlation between antigen density and ADC efficacy depends on the type of cancer cells (Polson et al., 2011; Kung Sutherland et al., 2013) due to varying internalization rate of each antigen after formation of a complex with an ADC molecule.