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where the first inequality holds due to the monotonicity and concavity of the model in (15), and the optimality of ∑ u ∈ U P u TP in (16), and the second inequality holds due to feasibility of a solution to the problem in (16) for the problem in (17).
Tissue-specific cytokine profiling is one approach to diagnosing disease severity, however utility of identified factors as biomarkers of disease is low due to feasibility of repeated sample collection.
Both Cox-MDR and Cox regression model have great advantages over Surv-MDR due to feasibility of adjusting for covariate.
We also could not validate the optimised algorithm on a different patient sample due to feasibility of medical record review, which therefore, may also impact the generalisability of the case capture.
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Due to feasibility 50% of gastroenterologists and general practitioners (25% within each group) were then randomized using computer generated random numbers.
Confounders like sociodemographic characteristics, bullying, class climate and leisure time behaviour were also assessed at baseline; stable traits like characteristics of personality and general parenting style will be assessed post-test, due to feasibility (especially length of questionnaire and time needed for completion).
Due to feasibility and the convenience of the volunteers, the period of active cooling was set at six hours.
However, for a few episodes, due to feasibility, only one set of blood culture was collected.
Recently, various indirect markers of oxidative stress have been used in epidemiological studies to measure oxidation damage due to feasibility and cost issues, instead of direct measures of free radicals and reactive oxygen species, which include electron resonance or spin trapping, capturing free radical reactions in real time (19).
Likewise, quasi-experimental designs are effective at evaluating the efficacy of interventions and may be preferred due to feasibility, and the practical challenges of conducting a controlled design [18].
Diagnoses from the ED were coded for a random sample of 22.7% due to feasibility reasons, and showed morbidity rates comparable with previous studies in similar settings [ 3, 10- 12, 37], suggesting that the randomisation was representative for the whole collective.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com