Sentence examples for due to elevated expression from inspiring English sources

Due to elevated expression levels, the p65 fusions were predominantly located in the nucleus for all constructs as can be inferred from figure 4 (panel b and e).

In TE671 cells, the Eps15-DN rather enhanced the CD4-dependent HIV-1 vector infection provably due to elevated expression of CXCR4 (Fig. 11C).

Our current findings suggest for the first time that proteasome-mediated protein degradation is impaired in A-T cells due to elevated expression of the ISG15 conjugation pathway, which could contribute to progressive neurodegeneration in A-T patients.

These results point instead to the possibility that overexpression of Msn2 targets inhibits rapamycin sensitivity due to elevated expression of some of its target genes, and that these do not inhibit TOR signaling akin to Hsf1 target genes.

Accelerated tumorigenesis in this model is due to elevated expression of iNOS, leading to the formation of oxidative DNA lesions.

These increases are predominantly thought to be due to elevated expression of the proteolytic enzyme MMP-2 [29]– [35].

Thirdly, when Osx could not be repressed in p53−/− osteoblasts, which showed enhanced differentiation due to elevated Osx expression [16], osteoblast differentiation was refractory to the inhibitory effect of the PAT inhibitor.

The former construct, pTLv6:Hsp90 was used as control to exclude gene dosis effects due to elevated Hsp90 expression.

This difference may be due to the increased toxicity of Tau in the previous study due to elevated Tau expression, which could potentially affect the recognition of Tau by endogenous kinases.

As NF-κB activation is commonly observed in breast cancers [ 24, 25, 49] and UEV1 upregulation is also frequently observed in breast cancer samples [ 12- 14] and in cultured tumor cell lines [ 4], and is found to be correlated to tumorigenic indicators [ 2, 3], it is conceivable that a certain percentage of breast cancer samples with NF-κB activation is due to elevated UEV1A expression.

As shown in Figure 2A, due to elevated basal expression of MT1-MMP in SK-N-SH cells, overexpression of WT MT1-MMP in these cells had a relatively low stimulatory effect on cell migration while the Y573F mutant strongly diminished both cell migration and MT1-MMP phosphorylation.