Sentence examples for due to efficacy from inspiring English sources

The quality of a remanufactured product induces hesitation for many people due to efficacy and reliability concerns.

Currently, the attritions of drugs are 51% due to efficacy, and 20% for safety, in relation to as low as 1% due to pharmacokinetic properties[11].

In the UK, despite equivalence with respect to the costs of three alternatives, both risperidone and olanzapine were cost-effective when compared with haloperidol due to efficacy gains [48].

In this regard, compounds that have passed through phases II or III in the drug discovery pipeline but never made it to the market due to efficacy issues bear great potential for drug repositioning approaches.

Despite considerable efforts to improve the pharmacokinetic profiles of small-molecule drug candidates, overall attrition rates remain high mainly due to efficacy, safety issues, and selection of inappropriate drug targets [1 3].

However, this assumption is now in question, with the high failure rate during the late stage of clinical trials due to efficacy and clinical safety problems (Xie et al. 2011) being the main source of the scrutiny.

Other efficacy/effectiveness measures included mean change in Positive and Negative Syndrome Scale (PANSS) [ 13] total, positive, and negative scores; time to all-cause discontinuation; rate of overall discontinuation; and rate of discontinuation due to efficacy-related reasons.

The NNT for discontinuation due to efficacy-related reasons was 8 (95% CI: 5 to 18) for high versus low dose and 13 (95% CI: 8 to 46) for high versus medium dose.

Figure 5 presents discontinuation rates, both overall (low: 36%, medium: 30%, high: 24%, p =.037) and due to efficacy-related reasons (low: 20%, medium: 14%, high: 6%, p <.001).

Among the various solutions proposed, the air-bubble curtain is often applied due to its efficacy in noise reduction.

Viruses are used extensively in the neuroscience community due to their efficacy and ease of engineering.