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In this context, the prevalence rate of neurocognitive impairment in HIV infected patient differs substantially among studies due to different methodological approach and study population [ 17].
Despite our higher harvest scenario seems similar to the one followed in the EU Reference Scenario [20], results for HWP are not comparable due to different methodological assumptions.
It has been shown that high throughput technologies, although valuable, often result in a large number of false positives due to different methodological artifacts.
This is partly due to different methodological issues.
However, due to different methodological approaches, the cortisol values tend to vary.
Meta-analyses have been difficult to perform due to different methodological approaches, treatment modalities and rehabilitation programs.
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Studies on the relationship between substance abuse and HIV disease progression reached different conclusions, probably due to different study designs and methodological limitations [29], [30], [48].
Harmonization of baseline variables, such as physical activity and education, had some methodological challenges due to different questionnaires in Norway and Denmark, which may have resulted in some imprecisions in these variables.
A closer examination of the original papers, however, shows that a large part of the numerical differences between Horiuchi-Coale and Mitra were, in fact, due to different inputs used in their calculations rather than methodological differences.
Only two of the primary studies were included in all of the reviews due to different inclusion criteria relating to publication date and status, definition of Pilates, and methodological quality.
Some other methodological limitations must be noted: The quality of data might be limited due to different interviewers and settings and due to missing data on health state in 24 of the 136 children.
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