Sentence examples for due to destabilizing from inspiring English sources

Numerically simulating deformations in thin elastic sheets is a challenging problem in computational mechanics due to destabilizing compressive stresses that result in wrinkling.

Cinnamon extracts are known to increase Tristetraprolin mRNA and protein levels, Tristetraprolins have anti-inflammatory effects due to destabilizing of pro-inflammatory mRNA [ 85].

This could be of benefit, for instance, in the treatment of selected cases of Lowe Syndrome due to destabilizing missense mutations in OCRL that may be rescued by chemical chaperones.

The faded green leaf (fgl) is a loss-of-function osporB mutant that displays necrotic lesions and variegation in the leaves due to destabilized grana thylakoids, and has increased numbers of plastoglobules in the chloroplasts.

Hyperphosphorylated tau dissociates from microtubules (35– 37), leading to the hypothesis that synaptic impairments and neurodegeneration are due to destabilized microtubules in axons.

Hyperphosphorylated tau dissociates from microtubules (35– 37), and synaptic impairment and neurodegeneration have been hypothesized to be due to destabilized microtubules in axons.

We also used the R163STOP protein in both these amorphous aggregation assays to assess its relative chaperone ability compared to the wild-type protein, but due to its destabilized structure only a limited number of assays could be performed.

Functional studies showed that these mutant receptors retain DNA binding but exhibit significant impairment of transcriptional activation and coactivator recruitment in response to different ligands (Barroso et al., 1999; Agostini et al., 2004), due to the mutations destabilizing the carboxyterminal α helix of PPARγ (Kallenberger et al., 2003), which mediates these functions.

(8 ) The Afghan War has also contributed to destabilizing Karachi.

Moreover, surface functionalization may also alter the intracellular localization of particles (Figure 5) as, for instance, PEI is commonly used as a nonviral gene transfection agent due to its ability to destabilize endosomal membranes and promote endosomal escape[29].

These results suggest that most of the epistasis that we identified during NP's evolution is due to counterbalancing stabilizing and destabilizing mutations.