Established strategies for cartilage and bone repair, such as autologous chondrocyte transplantation (ACT) (Ref. 1) and bone grafting (Ref. 2), have reached broad clinical application and yield satisfactory results due to continuous improvement.
Furthermore, the cost-effectiveness of sequencing is rapidly increasing and so is the accuracy due to continuous technical improvements, including some bench-top sequencing platforms [ 36].
The presented characteristics of the mentioned tools are expected to rapidly change due to the continuous improvements both in software and hardware development and do not comprise an exhaustive description of the discussed software's features.
Due to the continuous improvements in the biotechnological industry processes, several guidelines have been published to ensure that potential modifications associated with those developments, both within and among manufactures, do not have or potentially alter the pharmacological behavior or induce adverse effects on patients [ 4– 6].
Consequently, the hybrid 3T MR-BrainPET has emerged as an excellent tool for a wide spectrum of PET studies of the human brain due to the continuous improvements, which have successfully addressed the issues of quantification, optimising image quality and workflow.
Further, due to the continuous improvements of the PacBio system in terms of quality, read length and throughput, the potential for multiplexing is likely to increase, thus leading to substantial reductions in experimental cost.
However, merging diverse data types in the genome often becomes a time-consuming task due to the continuous improvement of the underling technologies and certain format incompatibilities.
