In this group the most common birth defect was undescended testicle with a BPR of 9.36/10,000 births, followed by unilateral cleft palate with a BPR of 5.32, patent ductus arteriosus with a BPR of 2.97 and unilateral cleft palate with a BPR of 2.72.
Premature closure of the fetal ductus arteriosus with resultant pulmonary hypertension has been noted in association with third trimester use of NSAIDs [ 25].
The evidence already available recommends (Class II, level A) a note of caution with regard to the consumption by women in the third trimester of pregnancy of foods with high concentrations of polyphenols, to avoid triggering constriction of ductus arteriosus, with its potential harmful consequences, such as fetal and neonatal heart failure and pulmonary arterial hypertension of the newborn.
Association of patent ductus arteriosus with ureaplasma colonization was more statistically significant (p = 0.0004) in patients with RDS than in those without RDS.
A 26-day-old neonate with a body weight of 3.7 kg was admitted to our hospital with diagnoses of d-transposition of the great arteries, restrictive patent foramen ovale, intact interventricular septum, patent ductus arteriosus with the use of prostaglandin E1, and pulmonary bicuspid valve.
How to submit the control group to the risk of keeping the ductus constricted, with all its potential complications?
In human patients with TGA a VSD is the second most common concomitant cardiac malformation after a persistent ductus arteriosus with an incidence of approximately 45% [ 19].
There are several methods to assess the haemodynamic significance of the ductus arteriosus, with ductal size being one of the most frequently used parameters.
Sixteen subjects that otherwise would have participated were excluded because of surgical closure of ductus arteriosus with a clip of unknown composition.
Other factors that have been associated with apnea in premature infants include glucose or electrolyte imbalance [ 85], as well as the presence of a patent ductus arteriosus with a large shunt [ 58].
