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Cysteamine hydrochloride (CSH) has also been shown to have such dual efficacy, but whether it affects rumen fermentation directly or indirectly by modifying digesta kinetics is unknown.
Combined with the previous work, the study shows that the Marburg vaccine has potential "dual efficacy," both as a preventive and a postexposure treatment, the team reports online today in The Lancet.
Several β-adrenoceptors have been shown to activate different downstream signalling ("dual efficacy ligands" e.g. human β2 [41] [42] and mouse β3 [43] but this is different from the high affinity/low affinity states of the β1 and β3-adrenoceptors outlined above.
These observations suggest that substance-P analogues act as dual efficacy receptor agonists directing receptor signalling via the GRP and the V1A receptor towards ERK activation while blocking liberation of intracellular calcium.
7 It was only once the wide-ranging roles of serotonin and noradrenaline in the central and peripheral nervous systems were understood that a common neuro-biochemical etiology could be appreciated, and the dual efficacy of duloxetine in depression and pain plus incontinence could be explained.
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Some of the provided scaffolds indicated dual anti-HIV efficacies against HIV reverse transcriptase and integrase enzymes at both cites as 3′-processing 3′-processingandfer, while strandl scaffolds exhibitransferncy against Raltegravir resistant HIV mutant strains determining themselves a potent class of compounds having appealing upcoming implementations.
To determine the efficacy of dual Y-shaped covered airway stents to treat thoracic stomach right main bronchus fistulae.
The results may also provide a rationale for the apparent superior clinical efficacy of dual uptake inhibitors.
Furthermore the efficacy of dual agent nanoparticles to induce apoptosis and inhibit migration of breast cancer cells was assessed by Annexin-V and wound healing assays respectively.
Furthermore the efficacy of dual agent nanoparticle to induce apoptosis and inhibit migration of colorectal cancer cells were assessed using Annexin-V and wound healing assays, respectively.
Few studies have investigated the efficacy of dual therapy with epinephrine injection plus either heat probe or argon plasma coagulation for high-risk bleeding peptic ulcers.
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