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Exact(13)
No ≥ grade 3 toxic effects to drug were observed.
Statistically significant increases in the solubility, dissolution and bioavailability of the drug were observed.
No obvious change in particle size and chemical degradation of drug were observed.
Sub-inhibitory concentrations of the released drug were observed in the medium only during the last two days of the experiment (minimized risk of occurrence of drug-resistant strains).
Common adverse events of each drug were observed in this study.
No adverse effects related to the drug were observed in any subject during the study period.
Similar(47)
The optimal effect of this drug is observed in the first 3 hr of use [28].
Initial burst release of drug was observed until 12 h and then drug release profile was relatively continuous manner.
Unexpected release of free drug was observed during the stability testing of an antibody drug conjugate (ADC).
An obvious burst release (>90%) of drug was observed in the simulated tumor microenvironment with MMPs and reductive glutathione.
The drug is observed to impart a stabilizing effect at low doses and a destabilization above a saturation level at the polar regions of the lipids.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com