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In addition to investigations examining the effects of the recent economic recession, there is a large literature examining how prescription drug utilization changes based on the prices that individuals are exposed to.
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Since rates of prescription drug utilization change over time based on secular and seasonal trends, all models controlled for these trends by including dummy variables for year (2008 as reference) and season (summer as reference).
Drug use changes the brain.
Results from these analyses show that across the diabetic population there have been major changes in drug utilization during this period, and these changes are associated with differences in mortality risk.
This paper examines changes in drug utilization following Taiwan's newly implemented National Health Insurance (NHI) outpatient prescription drug cost-sharing program for persons over 65 years old.
Incremental changes in drug utilization attributable to the effect of mail order were estimated.
Using interrupted time series analysis, we will study longitudinal changes in drug utilization and costs, medication adherence, and short-term health care use.
Using Interrupted Time Series Analysis, we will study longitudinal changes in drug utilization and costs, medication adherence, and ambulatory care visits and hospitalizations during each study month [ 33].
This effect might be important for early mortality, whereas changes in drug utilization after diagnosis may be more relevant for later mortality after the first 2 years.
Calculated p values from the Wilcoxon-Mann-Whitney test may overstate the significance of changes in drug utilization over time in the presence of clustering in the data, such as might occur if there were a tendency for differences in prescribing practices among hospitals.
18 Therefore the overall prevalence of prescription drug use among women giving first birth is underestimated and caution about conclusions regarding the observed change of drug utilization patterns in specific ATC-groups, eg neurological drugs, need to be considered.
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